Allakos Announces Multiple Presentations Related to Eosinophil and Mast Cell-Driven Diseases at the 2021 DDW Annual Meeting
The presentations will take place during the DDW Annual Meeting being held virtually from
Prevalence Data Presentations:
Presentation (Presenter): |
Endoscopy and Systematic Biopsy of Patients with Chronic Gastrointestinal Symptoms Leads to High Discovery Rate of Patients Who Meet Histologic Criteria for Eosinophilic Gastritis and/or Eosinophilic Duodenitis ( |
Session (Time): |
Novel Insights into the Pathogenesis and Management of Eosinophilic Esophagitis and Gastroenteritis (Presentation #537, |
Poster (Presenter): |
Gastroduodenal Eosinophilia is Under-Appreciated in Eosinophilic Esophagitis (EoE) Patients with Functional Bowel Symptoms: A Real Life Experience ( |
Session (Time): |
Eosinophilic Esophagitis and Gastroenteritis: Clinical (Session #5105, |
Long-Term Treatment Presentation:
Presentation (Presenter): |
Long-Term Treatment of Patients with Eosinophilic Gastritis and/or Eosinophilic with Lirentelimab, a Monoclonal Antibody Against Siglec-8 ( |
Session (Time): |
Novel Insights into the Pathogenesis and Management of Eosinophilic Esophagitis and Gastroenteritis (Presentation #539, |
Mechanism of Disease Presentation:
Poster (Presenter): |
Activated Mast Cells and Eosinophils are Associated with Increased Inflammatory Mediators in Mucosal Biopsies from Patients with Chronic Gastrointestinal Symptoms ( |
Session (Time): |
Eosinophilic Esophagitis and Gastroenteritis: Clinical (Poster of Distinction, Session #5105, |
Diagnosis of EG and/or EoD Presentations:
Poster (Presenter): |
Optimization of Eosinophilic Gastritis/Duodenitits Detection Requires Evaluation of Multiple High-Powered Fields in Each of 8 Gastric and 4 Duodenal Biopsies: Analysis from a Randomized Trial ( |
Session (Time): |
Eosinophilic Esophagitis and Gastroenteritis: Clinical (Session #5105, |
Poster (Presenter): |
Eosinophilic Gastritis and Eosinophilic Duodenitis Exhibit a Similar Clinical Presentation, Underscoring the Need for Collection of Multiple Biopsies from Both the Stomach and Duodenum to Evaluate for Tissue Eosinophilia: Analysis from a Randomized Trial ( |
Session (Time): |
Eosinophilic Esophagitis and Gastroenteritis: Clinical (Session #5105, |
Poster (Presenter): |
Endoscopic Appearance Does Not Predict the Presence of Histologic Eosinophilic Gastritis Among Symptomatic Adults, Indicating that Collection and Evaluation of Biopsies Should Occur Regardless of Endoscopic Appearance: Analysis from a Randomized Trial ( |
Session (Time): |
Eosinophilic Esophagitis and Gastroenteritis: Clinical (Session #5105, |
Following the presentations, the posters and slides will be available on the
About
Allakos is a clinical stage biotechnology company developing antibodies that target immunomodulatory receptors present on immune effector cells involved in allergic, inflammatory, and proliferative diseases. The Company’s lead antibody, lirentelimab (AK002), is being evaluated in a Phase 3 study in eosinophilic gastritis (EG) and/or eosinophilic duodenitis (EoD) and a Phase 2/3 study in eosinophilic esophagitis (EoE). Lirentelimab targets Siglec-8, an inhibitory receptor selectively expressed on human mast cells and eosinophils. Inappropriately activated eosinophils and mast cells have been identified as key drivers in a number of severe diseases affecting the gastrointestinal tract, eyes, skin, lungs and other organs. Lirentelimab has been tested in multiple clinical studies. In these studies, lirentelimab eliminated blood and tissue eosinophils, inhibited mast cells and improved disease symptoms in patients with EG and/or EoD, EoE, mast cell gastrointestinal disease, severe allergic conjunctivitis, chronic urticaria and indolent systemic mastocytosis. For more information, please visit the Company's website at www.allakos.com.
Source: Allakos Inc.
Investor Contact:Adam Tomasi , President, COO & CFO ir@allakos.com Media Contact:Denise Powell denise@redhousecomms.com
Source: Allakos Inc.