United States securities and exchange commission logo May 25, 2022 Meg Fitzegeral General Counsel, Secretary and Chief Compliance Officer Allakos Inc. 825 Industrial Road, Suite 500 San Carlos, CA 94070 Re: Allakos Inc. Registration Statement on Form S-3 Filed May 19, 2022 File No. 333-265085 Dear Ms. Fitzegeral: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Doris Stacey Gama at 202-551-3188 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: William Brentani, Esq.